Opposite the new port buildings, on Mizingani Road, this is a grand four-storey building with a set of particularly decorative balconies. It is also called the ithnasheri dispensary, and lettering at the top of the front wall reads 'Khoja Haji Nasser Nur Mohammed Charitable Dispensary'.

It was originally built in the 1890s as a private house for a prominent Ismaili Indian merchant called Tharia Topan, who was a customs advisor to the sultans, and one of the wealthiest individuals on Zanzibar at the time. In 1899 he gave the house up to be used as a dispensary, also funding the medicine and other services. Topan also provided money (with the Aga Khan and Sultan Ali) for a non-denominational school which opened in Zanzibar in 1891.

The dispensary fell into disrepair during the 1970s and 1980s, but was renovated in 1995 with funding from the Aga Khan Charitable Trust. A few years later it opened as the Stone Town Cultural Centre. There is a small exhibition (free) of historical photographs, but most of the building is now used as offices. More businesses are due to open here in the future.